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Smith et al. (1998) studied the influence on muscle metabolism during exercise in a placebo-controlled clinical trial

Short-term Creatine supplementation significantly improves maximal dynamic strength (bench (4.1 ± 1.4 kg) and leg press (16.1 ± 4.4 kg)) and maximal isometric strength (left and right knee extension) in men average age 65.4 ± 1.5 years

Creatine supplementation significantly increased body mass, fat-free body mass, lower-body mean power and lower-extremity functional capacity. Creatine supplementation significant increased (7-15%) maximal dynamic strength of large muscles of the hip/knee extensors (leg press) and chest and shoulders (bench press) as well as maximal isometric strength of smaller muscles of the quadriceps (knee extensions) and hamstrings (knee flexion).