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Tarnopolsky et al. (2001) studied
in a double-blind, placebo-controlled clinical trial in the elderly
the effects of long-term Creatine supplementation on the
Phosphocreatine and total Creatine levels, body composition and
strength
14 elderly men (67.8 ± 4.0 years) and 14 women (69.3 ± 6.3 years)
took either 5 g of Creatine Monohydrate or placebo during a 4 month
supervised strength-training program.
Creatine supplementation resulted in a
significant increase in muscle Phosphocreatine and total Creatine,
fat-free mass and isometric knee extension strength.
Similar results could be achieved by the loading phase / maintenance
phase supplementation program by Chrusch et al. (2001) in a similar
age group (70.4 ± 1.6 years). 4 months of
Creatine supplementation resulted in a significant increase in
muscular strength (leg press) and endurance (leg press and knee
extension)
Creatine supplementation is able to restore Phosphocreatine and
total Creatine levels and is able to speed up the
re-synthesis rate of Phosphocreatine in
the muscle of elderly people to a level not different from young
people.
Creatine supplementation increased body mass,
fat-free body mass, maximal dynamic strength, maximal isometric
strength as well as lower-body mean power and lower-extremity
functional capacity. |